Browsing Facultad de Medicina Humana by Author "Acosta, Oscar"
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Genetic ancestry of families of putative inka descent
Sandoval, José R.; Lacerda, Daniela R.; Jota, Marilza S.; Elward, Ronald; Acosta, Oscar; Pinedo, Donaldo; Danos, Pierina; Cuellar, Cinthia; Revollo, Susana; Santos, Fabricio R.; Fujita, Ricardo (Springer-Verlag GmbH Alemania, 2018-03-03)Acceso abiertoThis study focuses on the descendants of the royal Inka family. The Inkas ruled Tawantinsuyu, the largest pre-Columbian empire in South America, which extended from southern Colombia to central Chile. The origin of the ... -
Mutational analysis of BRCA 1 and BRCA 2 genes in Peruvian families with hereditary breast and ovarian cancer
Buleje, Jose; Guevara-Fujita, Maria; Acosta, Oscar; Huaman, Francia D. P.; Danos, Pierina; Murillo, Alexis; Pinto, Joseph A.; Araujo, Jhajaira M.; Aguilar, Alfredo; Ponce, Jaime; Vigil, Carlos; Castaneda, Carlos; Calderon, Gabriela; Gomez, Henry L.; Fujita, Ricardo (Wiley Periodicals, Inc., 2017-06-28)Acceso abiertoBackground Breast cancer is one of the most prevalent malignancies in the world. In Peru, breast cancer is the second cause of death among women. Five to ten percent of patients present a high genetic predisposition due ... -
The current genomic landscape of western south america: andes, amazonia, and pacific coast.
Sandoval, José R.; Acosta, Oscar; Zurita, Camilo; Aguilar-Campos, Abraham; Tito-Álvarez, Ana M.; Serrano-Osuna, Ricardo; Gray, Russell D.; Mafessoni, Fabrizio; Heggarty, Paul; Shimizu, Kentaro K.; Fujita, Ricardo; Stoneking, Mark; Pugach, Irina; Fehren-Schmitz, Lars (Society for Molecular Biology and Evolution, 2019-12)Acceso abiertoStudies of Native South American genetic diversity have helped to shed light on the peopling and differentiation of the continent, but available data are sparse for the major ecogeographic domains. These include the Pacific ... -
Tracing the genomic ancestry of Peruvians reveals a major legacy of pre-Columbian ancestors
Sandoval, Jose R.; Salazar-Granara, Alberto; Acosta, Oscar; Castillo-Herrera, Wilder; Fujita, Ricardo; Pena, Sergio D. J.; Santos, Fabricio R. (Springer Nature Limited, 2013-07-18)Acceso abiertoIn order to investigate the underlying genetic structure and genomic ancestry proportions of Peruvian subpopulations, we analyzed 551 human samples of 25 localities from the Andean, Amazonian, and Coastal regions of Peru ...